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Finding a home or condo for sale in Big Pine and the Lower Keys has never been easier! Instantly search our advanced database for single-family homes, waterfront homes, condos, townhouses, and commercial properties. New Lower Keys listings are added daily to ensure that you receive up-to-date information about available real estate in the Lower Keys area. You’ll find homes that meet your unique criteria, whether you’re looking for a vacation rental or a waterfront property.